Investigate Lymphangiogenesis in Carcinoma of Rectum of Human and Cancer Metastasis
- VernacularTitle:VEGF-C/Flt-4和Podoplanin在人直肠癌淋巴管生成中的表达
- Author:
Lijie YAO
;
Lei SHEN
;
Yang JIANG
- Publication Type:Journal Article
- Keywords:
Vascular endothelial growth factor;
Lymphatic vessel endothelial;
Adenocarcinoma of rectum
- From:
Journal of Medical Research
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of vascular endothelial growth factor-C(VEGF-C)and VEGF-R3(fms-like tyrosine kinase-4,Flt-4)on lymphangiogenesis in adenocarcinoma of rectum.Methods A series of 32 adenocarcinoma of rectum were detected for the expression of VEGF-C and VEGF-R3(fms-like tyrosine kinase-4,Flt-4)and Podoplanin by immunohistochemical SABC methods.Results The density of lymphatic vessel in the perimeter of the adenocarcinoma tissue of rectum was much higher than in the interior(P
