Research progress on preparative parameters that influnce the characteristics of PLA/PLGA/PELA microspheres prepared by double emulsion method
- VernacularTitle:复乳法制备聚乳酸及其共聚物微球参数的研究进展
- Author:
Ziran WANG
;
Qiyong XU
;
Yanqing YE
- Publication Type:Journal Article
- Keywords:
polylactic acid;
microspheres;
double emulsion method;
preparative parameters
- From:
International Journal of Biomedical Engineering
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
At present PLA and its copolymer is a kind of most widely used biodegradable polymers to prepare microspheres because of its good biocompatibility. The double emulsion method is the most used technique for microspheres loade with water-soluble drugs, proteins and peptides. Microspheres with different particle size or release character could be used in different applications such as targeted drug delivery or long-acting drug delivery. The characters of microspheres are influenced by the preparative parameter. This article reviewed the preparative parameters that influence the character of microspheres.
