Development of cancer stem cell
- VernacularTitle:肿瘤干细胞的研究现状
- Author:
Jinjuan ZHANG
;
Jichang SONG
- Publication Type:Journal Article
- Keywords:
stem cell;
cancer;
cancer stem cell
- From:
International Journal of Biomedical Engineering
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
According to traditional theory tumor growth arised from the proliferation of all tumor cells, therefore management mainly aimed at the majority of the cells within cancer tissue. As a result, relapse and metastasis developed often, which caused treatment failure. It was stem cell that makes it possible to treat cancer radically and prevent it from relapsing and metastasizing by specifically killing targeted cancer stem cells and even some old concepts such as tumorigenesis mechanism, cell signaling pathways etc may need to be reevaluated, that raised great challenge to traditional oncotherapy. In this text the origin and existing evidence of cancer stem cell, it's relationship to common stem cell, clinical significance and prospect were reviewed.
