Expression of IGFBP-2 and its correlation with estrogen receptor, progesterone receptor in breast cancer
- VernacularTitle:乳腺癌组织中胰岛素样生长因子结合蛋白-2的表达及其与雌激素受体、孕激素受体相关性的研究
- Author:
Yang HE
;
Zhaoning JI
;
Lu WANG
- Publication Type:Journal Article
- Keywords:
breast cancer;
insulin-like growth factor binding protein-2;
estrogen receptor;
progesterone receptor
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05 ); the positive percentage of IGFBP-2 was statistically higher in breast cancer with metastasis in lymph node than those without metastasis in lymph node (P 0.05 ,r_s= 0.271 ). CONCLUSION: The expression of IGFBP-2 may play an important role in the progression, invasion and metastasis of breast cancer, and there is a positive correlation between the expression of IGFBP-2 and ER in breast cancer. It demonstrates that over expression of IGFBP-2 may be a reference to evaluate unfavourable prognosis of breast cancer.
