Comparison two kinds of projects treatment of patients with advanced NSCLC
- VernacularTitle:两种方案治疗晚期非小细胞肺癌的疗效比较
- Author:
Jun JIA
- Publication Type:Journal Article
- Keywords:
Cancer,non-small cell lung;
Antineoplastic combined chemotherapy protocols;
Curative effect
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy and side effects of NP and IAP regimens in treatment of ad- vanced non-small cell lung cancer(NSCLC).Methods 72 patients with advanced NSCLC who were randomly divid- ed in to group A(n=42)and group B(n=30)were treated individually with NP regimen and IAP regimen.Results In group A,the efficiency rate was 52.38%(22/42),primary treated efficiency rate was 63.16%(13/20),re- treated efficiency rate was 45.45%(10/22).In group B,the efficiency rate was 46.66%(14/30),primary treated efficiency rate was 62.50%(10/16),retreated efficiency rate was 35.71%(5/14).The retreated efficiency rate in group A was higher than that in group B(P<0.05).There was no significant difference in myelosuppression and in nausea and vomiting between the two groups(P>0.05).Conclusion Both NP and lAP are effective and tolerable regimens for advanced NSCLC patients,but it seems that NP is better for retreated patients.