Prevention of asymptomatic coronary intimal lesion by controlling the risk factors of coronary heart disease
- VernacularTitle:控制危险因素对无症状性冠状动脉内膜病变防治的研究
- Author:
Shumei MA
;
Tiejun LI
;
Ning GENG
- Publication Type:Journal Article
- Keywords:
Angioscopy;
Asymptomatic intimal lesion;
Hypertension;
Diabetes;
LDL-C
- From:
Chinese Journal of Practical Internal Medicine
2006;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the prevention of asymptomatic coronary intimal lesion by controlling the risk factors of coronary heart disease(CHD).Methods The relationship between the intimal lesion(such as yellow plaque、plaque rupture and/or thrombus formation)and risk factors(such as hypertension、diabetes、high blood LDL-C、blood pressure and blood sugar in patients with high blood LDL-C)was investigated in the non-culprit vessels of 120 patients with old myocardial infarction and stable angina pectoris by applying coronary angioscopy.Results Totally 155 non-culprit vessels in 120 patients were explored and the following findings were observed:(1) There are 80 cases(66.67%)of intimal lesion,40 cases(33.33%)without intimal lesion.(2)In the group with intimal lesion,the simple yellow plaque was observed in 30 cases(25.00%)and complex plaque in 50 cases.(3) In 120 patients,hypertension was observed in 69 cases(57.50%),high blood LDL-C in 79 cases(65.83%)and type 2 diabetes in 40 cases(33.33%).(4)The complex plaques was less common in patients whose BP was less than 140/90 mm Hg than in patients more than 140/90 mm Hg(P0.05).Conclusion The plaque rupture can be well prevented which can reduce the incidence of ACS if the high blood pressure、high blood sugar、high LDL-C are controlled to an ideal level.