Expression of inflammatory factors in coronary atherosclerosis and the relationship between the factors and coronary risk score
- VernacularTitle:冠心病炎症因子表达及其与冠状动脉病变危险分数的相关性
- Author:
Huiliang LIU
;
Yuhui HE
;
Yujie WEI
- Publication Type:Journal Article
- Keywords:
coronary disease;
intercellular adhesion molecule-1;
C-reactive protein
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investingate the role of inflammation in coronary atherosclerosis and the relationship between the inflammatory factors and coronary risk score. Methods 56 patients with acute coronary syndrome were studied, among them 26 cases were diagnosed as acute myocardial infarction (AMI) and 30 unstable angina pectoris (UAP). The study group was compared with a control group of 30 cases who were identified as normal by coronary angiography. The concentrations of serum sICAM-1 and hsCRP were determined by ELISA assay. The coronary risk score was recorded in patients with UAP. Results Serum sICAM-1 levels were significantly elevated in patients with AMI or UAP compared with that of control group, while higher hsCRP level was observed only in the patients with AMI compared with those with UAP and the control group. By linear regression analysis, only serum sICAM-1 levels were correlated with coronary risk score (r=0.445, P
