A Study on Cardiac Abnormalities in Patients with Ankylosing Spondylitis and Undifferentiated Spondyloarthropathy.
- Author:
Young Ho LEE
;
Jong Dai JI
;
Dong Kyu JIN
;
Chang Gyu PARK
;
Hong Seog SEO
;
Dong Joo OH
;
Gwan Gyu SONG
- Publication Type:Original Article
- Keywords:
Ankylosing spondylitis;
Undiff erentiated spondyloarthropathy Cardiac abnormalities
- MeSH:
Aortic Valve;
Aortic Valve Insufficiency;
Arthritis;
Bradycardia;
Electrocardiography;
HLA-B27 Antigen;
Humans;
Rheumatic Diseases;
Spondylarthropathies*;
Spondylitis, Ankylosing*;
Thorax;
Uveitis
- From:The Journal of the Korean Rheumatism Association
1997;4(1):52-59
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To investigate the frequency, type and severity of cardiac abnormalities in the patients with ankylosing spondylitis and undifferentiated spondyloarthopathy. METHODS: A history, clinical examination, standard 12 lead electrocardiography, two dimensional, M mode, and Doppler echocardiographies were performed on 19 patients with ankylosing spondylitis, 15 patients with undifferentiated spondyloarthropathy and 21 normal controls. RESULTS: 1) Cardiac abnormalities were detected in 8 patients(42.1%) with ankylosing spondylitis. 2) Cardiac abnormalities were detected in 8 patients(53.3%) with undifferentiated spondyloarthropathy including 2 patients with aortic valve abnormalities(mild aortic insufficiency, aortic valve thickening. 3) Cardiac abnormalities were detected in one (4. 8%) among normal controls (mild tricuspid regurgitation). 4) There were sinus bradycardias on electrocardiography in 2 patients among patients witn anl;ylosing spond!litis and in 1 patient among undifferentiated spondyloarthropathy. But there was no conduction disturbance in both groups. 5) The frequency of cardiac abnormality was higher in patients with ankylosing spondylitis and undifferentiated spondyloarthropathy than in normal controls. 6) The mean age, mean disease duration, presence of uveitis, peripheral arthritis, HLA-B27, enthesopathy, Schober test and chest expansion in the patients with ankylosing spondylitis and undifferentiated spondyloarthropathy with cardiac abnormalities were not different from those in the patients without cardiac abnormalities. CONCLUSION: The frequency of cardiac abnormality was higher in patients with ankylosing spondylitis and undifferentiated spondyloarthropathy than in normal controls. The frequency, type and severity of cardiac involvement in patients with ankylosing spondylitis were not different from those in patients with undifferentiated spondyloarthropathy.