Expression and Significance of Interleukin-13 Receptor ?2 mRNA in Gliomas
- VernacularTitle:IL-13R?2基因在脑胶质瘤的表达及意义
- Author:
Jianjian ZHANG
;
Weiming ZHENG
;
Zhipeng SU
- Publication Type:Journal Article
- Keywords:
Interleukin 13;
Receptor;
Glioma;
RT-PCR
- From:
Journal of Medical Research
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the relationship between IL-13R?2 and the tumorigenesis and progression of gliomas. Methods Expression level of IL-13R?2 mRNA was studied by Reverse Transcription-Polymerase Chain Reaction(RT-PCR) in 20 cases of glioma and 5 cases of normal brain tissue. Results There was no expression of IL-13R?2 mRNA in all cases of normal brain tissue, wherea 13 of 20 gliomas expressed IL-13R?2.There were specially significant difference between them(P0.05) between low grade gliomas and high grade gliomas, there was greatly significant difference(P
