The efficacy and safety of trimebutine maleate in the treatment of functional dyspepsia
- VernacularTitle:马来酸曲美布汀治疗功能性消化不良疗效观察
- Author:
Biliang CHEN
- Publication Type:Journal Article
- Keywords:
Functional dyspepsia;
Trimebutine maleate;
Intervention
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To validate the clinical safety and efficacy of trimebutine maleate in the treatment of functional dyspepsia(FD).Methods 64 patients with FD were recruited into the study and ramdomly divided into two groups,each 32 examples.The observed group was given trimebutine maleate 200mg,po,tid,and the matched group was given oryzanol 10mg po,tid.The treatment circumstance was recorded one day before the treatment,and once a week for two weeks.Results After 2 weeks observation,drug efficacy to the symptom of naupathia,abdominal pain,diarrhoea and constipation were 86.7%,90.4%,84.6% and 85.7%,respectively.The observed group had gross efficiency for 82%,with the machted group for 54.0%.No side effect was observed.Conclusion Trimebutine is an effective agent for treatment of FD,and has no obvious side effect.
