Dimerization of G protein-coupled receptors and its possible role in signaling trasduction
- VernacularTitle:G蛋白偶联受体二聚化研究进展
- Author:
Congfen ZHANG
;
Daiyin PENG
;
Qinglin LI
;
Zhiqiang CHI
;
Jinggen LIU
- Publication Type:Journal Article
- Keywords:
GPCRs;
dimerization;
receptor binding;
signal transduction
- From:
Chinese Pharmacological Bulletin
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
G-protein coupled receptors(GPCRs)belong to the biggest subfamily of transmembran receptors.Recently,more and more research has been suggested that the dimerization of GPCRs may regulate the physiological and pharmacological activity.With the development of biochemistry technology and molecular biology,a great progress has been achieved in the field of the dimerization of GPCRs.This article will generally demonstrate that the vital roles of the homodimerization and heterdimerization.
