Application of Flow Cytometer for Diagnosis and Prognosis of Tumors of the Salivary Glands
- VernacularTitle:流式细胞术在涎腺肿瘤诊断及预后中的应用
- Author:
Rui DUAN
- Publication Type:Journal Article
- Keywords:
Salivary tumor;
Flow cytometer;
DNA aneuploid;
DNA index;
S-phase proliferating rate
- From:
Journal of Medical Research
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective In order to investigate the ability of flow cytometer (FCM) to diagnose malignant tumor and evaluate prognosis of tumors in salivary glands, the DNA ploidy and cell cycle had been analysed and the association of these parameters with histologic grades, lymph node metastasis were studied. Methods The fresh tissues of benign tumor, mixed tumor and malignant tumor were detected by FCM. Results DNA aneuploid has not been detected in benign tumors; 44 cases of mixed tumor has been detected with DNA aneuploid nd with high SPF; it suggests that these cases have malignant trend; most of malignant tumor were detected with high aneuploid. DI was not correlated with lymph node metastases, but correlated with histologic grades (P
