Expression and significance of KAI1/CD82 gene in non-small cell lung cancer
- VernacularTitle:非小细胞肺癌组织中KAI1/CD82基因表达及意义
- Author:
Xiaojie XU
;
Tonghua MEI
- Publication Type:Journal Article
- Keywords:
KAI1/CD82;
NSCLC;
metastasis;
immunohistochemistry
- From:Journal of Third Military Medical University
2003;0(13):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of KAI1/CD82 in non-small cell lung carcinomas(NSCLC) and explore the mechanism of invasion and metastasis of tumor cells.Methods The S-P immunohistochemistry was used to detect the expression of KAI1/CD82 in 62 specimens of primary NSCLC and 22 specimens of lymph node metastatic tissues. Twenty specimens from the normal tissues adjacent to the tumor over 5 cm were used as negative controls.Results The expression level of KAI1/CD82 in NSCLC(32.26%) was lower than that in negative control tissues(85.0%) (P
