Characteristics of B-ultrasonic renal changes in chronic aristolochic acid nephropathy
- VernacularTitle:慢性马兜铃酸肾病患者的肾脏B超特征及其临床意义
- Author:
Yonghong ZHOU
;
Li YANG
;
Wei QIN
;
Haiyun QU
;
Xiaomei LI
- Publication Type:Journal Article
- Keywords:
Aristolochic acid;
kidney failure,chronic;
Nephritis, interstitial;
Chronic aristolochil acid nephropathy;
Ultrasonography;
Atrophy
- From:
Chinese Journal of Nephrology
2005;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the B- ultrasonic (B-US) renal changes of chronic aristolochic acid nephropathy (CAAN) patients and to determine its value in disease diagnosis. Methods The renal B-US data of 124 CAAN patients were retrospectively studied. The relationship between the B-US characteristics and the renal function was tested. Clinicopathological data of 19 CAAN patients underwent renal biopsy were compared with those of 18 patients with chronic tubulointerstitial nephropathy due to none-aristolochic acid causes (non-AAN-CTIN). Results The characteristics of renal B-US changes in CAAN patients included diminished parenchyma thickness (90.3%), atrophy of the kidney (62.90%) and asymmetrically shrinked kidneys (17.74%). The renal B-US markers, including the longitude, the volume and the parenchyma thickness, were closely associated with the level of Scr, eGFR and the function of renal tubules (P
