Hyperhomocysteinemia, Genetic Polymorphism of Methylenetetrahydrofolate Reductase and Cerebrovascular Diseases
- VernacularTitle:高同型半胱氨酸血症、MTHFR基因多态性与脑血管病
- Author:
Juan GAO
;
Li GUO
- Publication Type:Journal Article
- Keywords:
homocysteine;
methylenetetrahydrofolate reductase;
gene polymorphism;
cerebrovascular disease
- From:
International Journal of Cerebrovascular Diseases
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Hyperhomocysteinemia is one of the independent risk factors of cerebrovascular diseases. Methylenetetrahydrofolate reductase (MTHFR) C677T gene mutation often results in the increase of plasma homocysteine levels, but the relationship between the genetic polymorphism of MTHFR and cerebrovascular diseases is not significant.