The Immunological Characteristics of Central Nervous System and the Problems of Immunological Rejection of Neural Stem Cell Transplantation
- VernacularTitle:中枢神经系统的免疫学特性与神经干细胞移植的免疫排斥问题
- Author:
Suhua HU
;
Heng WU
;
Aiqun LIU
- Publication Type:Journal Article
- Keywords:
central nervous system;
neural stem cell;
immunological rejection
- From:
International Journal of Cerebrovascular Diseases
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
It is considered that the central nervous system (CNS) is an immunologically privileged organ, but its immunological privilege is not complete, and immunological rejection may also occurred after tissue transplantation. Neural stem cell (NSC) transplantation has developed a brand-new approach for the treatment of various CNS diseases. Despite the low immunogenicity of NSC, there are also troubles of immunological rejection. This article reviews the immunological characteristics of CNS, the mechanisms of immunological response and immunological rejection in CNS, as well as the problems of immunological rejection of NSC transplantation.
