INHIBITION OF GASTRIC CANCER CELLS INVASION AND METASTASIS BY GENISTEIN IN VITRO
- VernacularTitle:染料木黄酮对胃癌细胞侵袭转移的抑制作用
- Author:
Junwen ZHANG
;
Pilong WANG
- Publication Type:Journal Article
- Keywords:
gastric cancer cells;
genistein;
invasion and metastasis;
TGF- 1
- From:
Acta Nutrimenta Sinica
1956;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objetive: To study the effect of genistein on the invasion and metastasis of human gastric cancer cells SGC-7901 in vitro. Method: MTT was used to study the effects of adhesion by genistein on SGC-7901. The Boyden Chamber membrane invasion culture system was used to study invasion and metastasis. Cell-immunochemistry was used to observe the change of TGF- 1. Results: In the membrane invasion culture system, the numbers of invading and migrating SGC-7901 cells were significantly lower in genistein treated groups than those in the control groups (P
