Efficacy and safety of diclofenac sodium paste in the treatment of primary osteoarthritis of the knee
- VernacularTitle:双氯芬酸钠贴片治疗骨性关节炎的有效性及安全性研究
- Author:
Shuju SONG
;
Ting DUAN
;
Haohong LI
- Publication Type:Journal Article
- Keywords:
Osteoarthritis;
Diclofenac sodium paste;
Treatment outcome
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the efficacy and safety of diclofenac sodium paste in the treatment of primary osteoarthritis(OA).Methods 54 patients with primary OA were divided into two groups.The experiment group received diclofenac sodium paste.The control group received diclofenac sodium(votalin) emulgel.Patient global assessment and topical pain assessment,physician global assessment and topical pain assessment were wrote down at baseline and after final application.Safety was assessed by evaluation of adverse events,vital signs,and irritation at the application site.Results There were no significant difference between experiment group and control group in patient global assessment,patient pain assessment,physician global assessment,and physician pain assessment.No serious gastrointestinal or renal adverse events were reported or detected by means of laboratory testing.Conclusion Diclofenac sodium paste is effective and safe in the treatment of primary OA.
