Expression of KAI1 gene in cervical cancer and its clinical significance
- VernacularTitle:KAI1基因在宫颈癌组织中的表达及临床意义
- Author:
Xia LIN
;
Xiaoying XIONG
;
Lihua FU
- Publication Type:Journal Article
- Keywords:
Cervical neoplasms;
KAI1 mRNA;
The transcription-polymerase chain reaction;
Neoplasm-metastasis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of KAI1mRNA in cervical carcinoma and its clinical significance.Methods The transcription-polymerase chain reaction(RT-PCR) method was applied to detect the expression of KAI1mRNA in 53 fresh freezing cervical tissues.The findings were compared with the clinicopathological data.Results The expression of KAI1mRNA was (0.309?0.093) in normal cervix,(1.608?0.289) in cervical intraepithelial neoplasia(CIN),(0.948?0.910) in cervical carcinoma respectively.The relative densitometric value of KAI1mRNA decreased in late stage of cervical cancer in local cervical cancer with lymphatic metastasis(P
