Expression of MMP-9 mRNA in human hepatocellular carcinoma
- VernacularTitle:原发性肝癌基质金属蛋白酶-9的表达与肿瘤侵袭关系
- Author:
Hongdong ZHANG
;
Jian WANG
;
Bihong JI
;
Huaping XU
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Metastasis;
RT-PCR
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of MMP-9 genes in primary hepatocellular carcinoma(HCC).Methods RT-PCR was used to detect MMP-9 mRNA in surgically extracted specimens from 28 patients with HCC.Results The expression of MMP-9 mRNA was significantly higher in tumor than in corresponding nontumoral tissue(P0.05).Meanwhile,the expression of MMP-9 mRNA in HCC was significantly correlated to the existence of portal vein tumor thrombus(P
