Extracellular matrix of xenogenic femoral fascia for the repair of renal trauma
- VernacularTitle:将异体阔筋膜细胞外基质用于肾修补的实验研究
- Author:
Guanglin HUANG
;
Xiaofeng WANG
;
Liu LIU
;
Guizhong LI
;
Jianwei WANG
;
Libo MAN
;
Jie HU
- Publication Type:Journal Article
- Keywords:
Fascia lata;
Extracellular matrix;
Kidney;
Reconstructive surgical procedures;
Tissue engineering
- From:
Journal of Peking University(Health Sciences)
2004;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effect of extracellula matrix of xenogenic femoral fascia in repair of renal trauma. Methods: Twelve adult dogs were used and randomly assigned to 6 groups, and the animals were sacrificed separately in 1 and 2 weeks 1,2,4 and 8 months after renal repair operations. The examinations of blood and urine routine, blood urea nitrogen and creatinine, electrolyte and serum renin were performed before and after operations at various times. The creatinine clearances of affected and contralateral normal kidneys were evaluated before death and the local areas of renal repair were studied by light and electron microscopy. Results: Bleeding was stopped completely after the entire patch was sutured, and only mild adhesions to around tissues were found in various times after operations. As time passed, the repair patch was replaced by smooth neocapsule like normal renal capsule. Conclusion: Extracellula matrix of xenogenic femoral fascia might be an ideal tissue-engineering material for renal repair.
