Itraconazole against invasive fungal infection in patients of multiple organ dysfunction syndrome
- VernacularTitle:伊曲康唑在多器官功能障碍综合征患者侵袭性真菌感染中的应用
- Author:
Jianqiong XIONG
;
Zhaoxia DENG
;
Lei ZHANG
;
Liang WEN
;
Xianhui XIE
- Publication Type:Journal Article
- Keywords:
itraconazole injection;
multiple organ dysfunction syndrome;
fungal infection
- From:Journal of Third Military Medical University
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of itraconazole injection in treatment of invasive fungal infection in the patients with multiple organ dysfunction syndrome.Methods Invasive fungal infection in 15 patients with multiple organ dysfunction syndrome was treated with 200 mg itraconazole injection,twice a day on the first two days,then once a day,for 8 to 14 days.During the treatment,the symptoms and signs,the results of chemical detection were recorded.Everyday fungus,sputum,stool smear or culture were performed.Results The recovery rate,effective rate,and fungal clearance in this trial with itraconazole injection were 80%(12/15),86.7%(13/15),and 86.7%(13/15) respectively.The side effect was not found.Conclusion Itraconazole injection is an effective and safe drug against invasive fungal infection in patients with multiple organ dysfunction syndrome.
