The Mechanisms of Cerebral Vasospasm Caused by Subarachnoid Hemorrhage and Its Clinical Treatment Progress
- VernacularTitle:蛛网膜下腔出血致脑血管痉挛的机制和临床治疗进展
- Author:
Qi LIANG
;
Jinning SONG
- Publication Type:Journal Article
- Keywords:
subarachnoid hemorrhage;
cerebral vasospasm;
cerebral ischemia
- From:
International Journal of Cerebrovascular Diseases
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral vasospasm is one of the most severe complications of subarachnoid hemorrhage. Its incidence is as high as 30-90%. It often causes severe regional cerebral ischemia or delayed ischemic brain damage, even resulting in cerebral infarction, and it thus becomes the primary cause of mortality and disability. In recent years, with the development of studies, people have realized that the oxyhemoglobin, inflammatory reaction, accumulation of vasoconstrictive substances, apoptosis, blood hypercoagulability and blood vessel cell proliferation play important roles in the development of cerebral vasospasm. Although its mechanism remains unclear, better effects have been achieved by using related treatment methods according to the available pathogenesis.