Thrombin-Activatable Fibrinolysis Inhibitor and Ischemic Cerebrovascular Disease
- VernacularTitle:凝血酶激活的纤溶抑制物与缺血性脑血管病
- Author:
Xinggang SONG
;
Yanlu XU
- Publication Type:Journal Article
- Keywords:
thrombin;
fibrinolysis;
ischemic cerebrovascular disease;
thrombosis
- From:
International Journal of Cerebrovascular Diseases
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Thrombin activatable fibrinolysis inhibitor (TAFI), a novel regulator of coagulation and fibrinolysis, was discovered recently. The activated TAFI (TAFIa) makes fibrinolysin lose its action sites with fibrin, and thus exerts its fibrinolytic inhibition and promotes thrombosis. Making a thorough study of TAFI may provide a new option for the treatment of ischemic cerebrovascular disease.
