Expression of CDK4 and CyclinD1 in renal cell carcinoma and adjacent renal tissues
- VernacularTitle:肾细胞癌组织中CDK4、CyclinD1的表达及其意义
- Author:
Lixin SHI
;
Gang LI
;
Baofa HONG
- Publication Type:Journal Article
- Keywords:
renal cell carcinoma;
real-time fluorescence quantitative PCR;
CDK4;
CyclinD1
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the significance of the expression CDK4 and CyclinD1 in renal carcinoma. Methods Real-time fluorescence quantitative PCR method was used to detect the expression level of CDK4 and CyclinD1 in 30 specimens of renal carcinoma tissue and 30 specimens of carcinoma-adjacent renal tissue. Results The expression level of CyclinD1 and CDK4 gene in renal carcinoma tissue was higher than that in carcinoma-adjacent renal tissues (P
