A comparison between the effects of valsartan and benazepril,captopril on the excretion rate of urinary albumin and the clearance of endogenous creatinine in elderly hypertensive patients
- VernacularTitle:缬沙坦、苯那普利及卡托普利对老年高血压患者肾脏的保护作用
- Author:
Xiaoyuan TIAN
;
Juan WANG
;
Yuxiang ZHAO
- Publication Type:Journal Article
- Keywords:
Angiotensin-converting enzyme inhibitors;
Hypertension;
Aged
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of valsartan and angiotensin-converting enzyme inhibitors on the excretion rate of urinary albumm(UAER) and the clearance of endogenous creatinine(Cr-C) in elderly patients.Methods 120 elderly patients with stage of the 2～3 class hypertension were included.The patients were divided into 3 groups,the valsartan group and the benazpril group and captopril group,the anti-hypertensive effects and UAER and Cr-C were determined before and after the treatment.Results No significantly different anti-hypertensive effects were observed in valsartan,benazpril and captopril.But the effects of UAER,Cr-C in valsartan group had significant changes compared with the other groups,and the three groups had significant differentiation(P
