Study on Immunomodulation and Tumor-inhibition of Bifidobacterium Cell Wall in Mice.
- VernacularTitle:青春双歧杆菌细胞壁免疫调节和抑瘤作用研究
- Author:
Junjie GUO
;
Tao JANG
- Publication Type:Journal Article
- Keywords:
Bifidobacterium adolescence cell wall;
Macrophage;
IL-1;
IL-12;
TNF-?;
Tumor-inhibition
- From:
Journal of Medical Research
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the immunologic regulation of the bifidobacterium adolescence cell wall(BCW) on function of macrophage in mice and tumor inhibition of BCW on human transitional cell carcinoma of bladder(BTCC) outside of body.Methods BCW wereinjected into abdomen of KM mice,the level of IL-1,IL12 and TNF-?which produced by macrophage was determined by ELISA reagent box.The role of tumor inhibition was determined by MTT method.Results The level of IL-1,IL12 and TNF-?of BCW injection group was higher than of control group(P
