Montelukast,ketotifen combined with BCG-PSN decreased the incidence of asthma followig bronchiolitis
- VernacularTitle:口服孟鲁斯特、酮替芬加肌内注射卡介苗多糖核酸联合防治毛细支气管炎后哮喘的临床观察
- Author:
Da ZHENG
;
Jianwei HUANG
;
Xiaoshan CHEN
- Publication Type:Journal Article
- Keywords:
Bronchiolitis;
Asthma;
Drug therapy,combination
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficiency of montelukast and ketotifen combind with BCG-PSN(polysaccharide nucleic acid fraction of bacillus calmette guerin for injection) in decreasing the incidence of asthma following brochiolitis.Methods 30 patients with brochiolitis were given montelukast,ketotifen and BCG-PSN,compared with 31 patients with brochiolitis without the treatment.The total course were two months for oral montelukast,three months for oral ketotifen,and six months for injecting BCG-PSN.The time of follow up was over 1 year and the cases of patients developed asthma were investigated,serum level of IgE,IgA,IgG,IgM were tested before and after the treatment.Results After follow up 1 year,1/30(3%) of patents with brochiolitis receiving treatment developed asthma compared with 9/31(29%) of the controls with brochiolitis(P
