Therapeutic effect of treatment with surgery and mifepristone in patients with endometriosis
- VernacularTitle:手术联合米非司酮治疗子宫内膜异位症的疗效分析
- Author:
Huizhen ZHANG
- Publication Type:Journal Article
- Keywords:
endometriosis;
surgery;
mifepristone;
therapeutic effect
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2002;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To evaluate the therapeutic effect of treatment with surgery and mifepristone in patients with endometriosis. METHODS: The medical records of 126 endometriosis patients undergoing surgical operation were analyzed retrospectively. There were 28 cases in stage Ⅰ or Ⅱ, 73 cases in stage Ⅲ, and 25 cases in stage Ⅳ. Conservative surgery was performed in 96 cases and semi-conservative surgery in 30 cases. Postoperation, 92 cases continued taking 10 mg?d~ -1 of mifepristone for 6 months and 34 cases did not. All patients received 3 to 5 years follow up. RESULTS: The complete remission (CR) rate in mifepristone group was 77.2 %, partial remission (PR) rate was 22.8 %, and recurrence rate was 16.3 %. The CR of controls was 52.9 %, PR was 47.1 %, and recurrence rate was 32.4 %. There was significant difference between two groups (P
