FGF-13 expression in vibrissae follicle stem cells
- VernacularTitle:大鼠生长期触须毛囊干细胞中FGF-13的表达研究
- Author:
Min JIN
;
Tian YANG
;
Xiaohua LIAN
;
Yuanbin LI
- Publication Type:Journal Article
- Keywords:
fibroblast growth factor-13;
hair follicle;
stem cell
- From:Journal of Third Military Medical University
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression and distribution of fibroblast growth factor-13(FGF-13) in rat vibrissa follicle at anagen and the cultured cells derived from bulge region.Methods FGF-13 expression was detected using immunohistochemistry and immunocytochemistry.Results The in vitro cultured cells from bulge region and the vibrissa follicle expressed FGF-13.In vivo,the cells expressing FGF-13 distributed in the outermost layer of the outer root-sheath(ORS) in the isthmus portion of the follicle.No cells expressing FGF-13 were present in the hair follicle bulb,including matrix cells and ORS.Conclusion In vibrissa follicle at anagen FGF-13 may be involved in the migration of stem cells located at the bulge region to the hair bulb.
