Arachidonate 5-Lipoxygenase-Activating Protein and Stroke
- VernacularTitle:ALOX5AP与卒中
- Author:
Qingcheng LIANG
;
Qiang GAO
- Publication Type:Journal Article
- Keywords:
5-lipoxygenase-activating protein;
Stroke;
gene
- From:
International Journal of Cerebrovascular Diseases
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
5-lipoxygenase-activating protein Gene (ALOX5AP) on chromosome 13q12-13 encodes 5-lipoxygenase-activating protein (FLAP). The latter plays a key role in regulating the synthesis of leukotriene. Studies have suggested that the subjects who carry this gene may increase stroke risk by two times. Therefore, ALOX5AP plays an important role in the pathogenesis of stroke.
