Progress of nerve guidance channels incorporated neurotrophic factors
- VernacularTitle:复合神经营养因子的神经导管研究进展
- Author:
Zheng LI
;
Wei WANG
- Publication Type:Journal Article
- Keywords:
peripheral nerve;
nerve regeneration;
neurotrophic factors
- From:
International Journal of Biomedical Engineering
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
This review discusses several strategies that have been employed to enhance the regenerative effectiveness of artificial nerve guidance channels. These strategies include the use of scaffolds, the integration of contact-mediated cues within the tubular construct, and incorporation or delivery of exogenous growth factors into the conduit lumen uniformly or in a gradient form. Animal and clinical studies are reviewed to explain some of the ideas involved in developing a guidance channel of the future.