Tissue engineering heart valve and the prospect of stem cells for tissue engineering applications
- VernacularTitle:组织工程心脏瓣膜及干细胞应用前景
- Author:
Kang ZHOU
;
Xinmin ZHOU
- Publication Type:Journal Article
- Keywords:
tissue engineering;
heart valve prosthesis;
nuclear transfer;
seed cells
- From:
International Journal of Biomedical Engineering
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The tissue engineering heart valve(TEHV) is a kind of procthetic valve that possesses the characteristics of living, self-repair and proliferation. Owing to the specific properties that are the better hemodyna-mics, low or even no immunological reaction, no need for long-time anticoagulation therapy and longer durability, the ideal TEHV can overcome the drawback of current available valve substitutes which are mechanical prostheses and biological heart valves. In this paper we reviewed the recent development of the TEHV in such aspects, as biomaterial, cultivating environment, seed cells and so on. In addition, we briefly introduced the perspective of using human embryonic stem cells as the source for seed cells in TEHV.
