Effect of dexamethasone on conversion of subclinical hypothyroidism caused hy Hashimoto's thyroiditis
- VernacularTitle:地塞米松治疗桥本甲状腺炎的临床价值
- Author:
Zhong CHEN
- Publication Type:Journal Article
- Keywords:
Thyroiditis,autoimmune;
Dexamethasone;
Injections,intralesional;
Levothyroxine
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of oral levothyroxine plus intrathyroidal injection of dexamethasone on conversion of subclinical hypothroidism caused by Hashimoto's thyroiditis.Methods 80 subjects with Hashimoto thyroiditis were randomly divided into 2 groups.Subjects in levothyroxine group(40 cases) were treated with oral levothyroxine sodium,subjects in dexamethasone group(40 cases) were treated with oral levothyroxine plus intrathyroidal injection of dexamethasone.Serum free triiodothyronine(FT_3),free thyroxine(FT_4),sentient thyrotropin(sTSH) and other parameters were evaluated before treatment and after treatment in patients with Hashimoto's thyroiditis.Results The content of FT_3,FT_4 after treatment were obviously higher than that before treatment(t=2.123,P
