The effect on intestinal mast cell in rats of botulinum toxin-A by injection intraperitoneally
- VernacularTitle:腹腔注射A型肉毒毒素对大鼠肠道肥大细胞的影响
- Author:
Hui HAN
;
Qingsen LIU
;
Wenhui LIU
- Publication Type:Journal Article
- Keywords:
Botulinum toxin type A;
Mast cell;
Rats,Wistar
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigante the effect on the count of intestinal mast cell in rats of botulinum toxin-A.Methods 40 Wistar rats of 8 weeks age were divided into four groups randomly and evenly.4 units,2 units,1 unit BTA was injected in every rat peritoneally in group A,B,C.D was control group.The samples of small intestine,ileocecal junction and distal colon was stained with toluidine blue improved staining method for mast cell at 4 weeks after injection.Results The counts of mast cell in all the samples in group A and B[small intestine (5.16?2.74) and (4.50?3.19);ileocecal junction (3.83?1.78) and (3.33?2.50);distal colon (7.00?2.53) and (7.50?3.29),respectively] were smaller than those of group D[(11.16?4.48),(8.50?3.04),(13.66?4.83),P
