Relationship of the expression of transforming growth factor,vascular endothelial growth factor with angiogenesis in thyroid cancer
- VernacularTitle:转化生长因子?_1和VEGF在甲状腺癌组织中的表达及其与血管生成的关系
- Author:
Xiaobing WANG
;
Zhijun YI
;
Shuling ZHU
;
Qihuan GAN
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Transforming growth factor beta;
Vascular endothelial growth factors;
Microvessel count
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of the expressions of transforming growth factor ?_1(TGF?_1),vascular endothelial growth factor(VEGF) with angiogenesis in thyroid cancer.Method TGF?_1,VEGF and microvessel countt(MVC) were detected by immunohistochemical method in 46 thyroid cancer specimens.Results The mean MVC was significantly higher in tumors with positive TGF?_1 or VEGF than in tumors with negtive TGF?_1 or VEGF[(26.18?4.05) vs (20.13?4.29) for TGF?_1 and (25.82?3.61) vs (19.65?6.32) for VEGF,P
