Serum concentration change of sFas after ~(131)I therapy in patients with GD
- VernacularTitle:Graves病患者治疗前后血清可溶性细胞凋亡相关蛋白Fas的含量变化及其意义
- Author:
Xiaobing LIU
;
Yixiang FANG
- Publication Type:Journal Article
- Keywords:
Graves' disease;
Proteins;
Enzyme-linked immunosorhent assay;
Radiotherapy;
Iodine radioisotopes
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the serum concentration of serum Fas(sFas) in patients with Graves' disease(GD) before and after ~(131)I therapy.Methods Serum levels of sFas were measured with enzyme linked-immuno-sorbent assay(ELISA) in 61 patients before and after ~(131)I therapy,and the results were compared with that the control subjects.Results The concentration of sFas was significantly higher in GD patients compared with that in the control subjects[(174.8?94.6)ng/L vs (96.6?10.2)ng/L,P0.05],and was significantly lower in patients with euthyroidism after 131 I therapy[(111.2?13.2)ng/L,P
