The role of Ca~(2+) in the myocardial ischemic preconditioning
- VernacularTitle:钙离子在心肌缺血预适应中的作用
- Author:
Kang WANG
;
Wangkou MA
;
Xi WU
;
Hongyan LI
- Publication Type:Journal Article
- Keywords:
Ischemic preconditioning,myocardial;
Cytoprotection;
Myocardial reperfusion injury;
Calcium
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of Ca~(2+) in the mechanism of ischemic preconditioning effects.Methods Fifty Sprague-Dawley male rats were divided into 5 groups randomly:IC group,ischemic control,IP group,ischemia followed by reperfusion;IP+Verapamil group,Bay k8644 group,Verapamil group.Results Siginificant heart functional recovery was observed in IP group as campared with that in IC group(P
