Proceedings of TREK-1, a subtype of tandem-pore-domain potassium channels
- VernacularTitle:TREK-1双孔钾通道的功能研究进展
- Author:
Lina SUN
;
Xiaoliang WANG
- Publication Type:Journal Article
- Keywords:
tandem-pore-domain potassium channels;
neuroprotection;
anesthesia;
regulation
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Tandem-pore-domain potassium channels are a diverse and highly regulated superfamily of channels that are thought to provide baseline regulation of membrane excitability. Of these, TREK are highly expressed in human CNS. TREK can be regulated by both physical and chemical factors. Lately, study on knockout animals suggested that TREK-1 might participate in the process of general anesthesia of some anesthetics.
