The study of Th_1/Th_2 bias in Hashimoto thyroiditis
- VernacularTitle:桥本甲状腺炎Th_1/Th_2平衡偏移的研究
- Author:
Jinyuan MAO
;
Chenling FAN
;
Haixia GUAN
- Publication Type:Journal Article
- Keywords:
Hashimoto thyroiditis;
Th_1/Th_2;
CCR5;
CD30;
Flow cytometry
- From:
Chinese Journal of Practical Internal Medicine
2002;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the trend of Th_1/Th_2 bias in Hashimoto thyroiditis(HT)and their effects on the pathogenesis of HT.Methods The proportion and mean fluorescence intensity(MFI)of CCR5 and CD30 were examined on peripheral T lymphocytes by flow cytometry in patients with Hashimoto thyroiditis(HT)(n=21)and healthy controls(n=45).Results The proportion of both CD4~+CCR5~+and CD~+4 CD30~+ cells were significantly increased in HT group(P
