Research on mechanism of chaos during ventricular fibrillation induced by rapid pacing after acute myocardial infarction
- VernacularTitle:急性心肌梗死后快速刺激诱发心室颤动的“混沌机制”的研究
- Author:
He ZHANG
;
Zhijun SUN
;
Yingxian SUN
- Publication Type:Journal Article
- Keywords:
Acute myocardial infarction;
Period doubling bifurcation;
Quasiperiodicity;
Ventricular fibrillation
- From:
Chinese Journal of Practical Internal Medicine
2002;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the mechanism of chaos during ventricular fibrillation(VF)after acute myocardial infarction(AMI)and observe the property of nonlinear dynamics of VF in order to provide clinical doctors with theory evidences to prevent VF after AMI.Methods From Jun.2003 to Dec.2005,we made the acute myocardial infacrtion model and induced VF of canine in vivo by using rapid pacing,and recorded the cardiac electrophysiological parameters by using 64-trains multi-polar epicardial-mapping electrocardiogram system to observe the change of the cycle length(CL)of ventricular arrhythmia in the Second Affiliated Hospital of China Medical Univercity.Results The pacing interval of VF in acute ischemia myocardium had been significantly increased; the cycle length(CL)showed the spatiotemporal complexity,such as period doubling bifurcation and quasiperiodicity and its Poincar'e plots formed a ring-like structure meaning nonlinear dynamics property during VF.Conclusion The liminal value of VF has been significantly increased during acute myocardial infarction.VF is induced by system come-into period doubling bifurcation,quasiperiodicity and chaos.
