Experimental research of mice infected with Schistosoma japonicum cercariae by different ways
- VernacularTitle:日本血吸虫尾蚴经不同途径和方式感染的研究
- Author:
Qianhong XIE
;
Xiao ZHANG
;
Lan ZHANG
;
Youen SHI
- Publication Type:Journal Article
- Keywords:
Schistosoma japonicum cercariae;
Indirect ELISA;
IgG antibody;
Infection way
- From:
Chinese Journal of Schistosomiasis Control
1989;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility of establishing animal model of schistosomiasis through subcutaneous injection of IMDM liquid and intramuscular injection of IMDM liquid both of which contained the cercariae.Methods The mice were infected with schistosome cercariae by three different ways: subcutaneous injection(Group A),intramuscular infection(Group B) and the classical method: skin infection(Group C).Forty-five days post-infection, the mice were sacrified and the adult schistosomes were investigated. The serum IgG antibodies were detected by indirect ELISA in 15 and 45 days after infection. Results The recovery adult worm rates were 39.2% in Group A,32.3% in Group B and 72.8% in Group C,and there was a significant difference among them (P
