Fibrin(ogen), Its Degradation Products and their Motif Antagonist and Atherosclerosis
- VernacularTitle:纤维蛋白(原)、纤维蛋白(原)降解产物及其基序拮抗剂与动脉粥样硬化
- Author:
Yongjun CAO
;
Jinjun QIAN
;
Chunfeng LIU
- Publication Type:Journal Article
- Keywords:
fibrin(ogen);
fibrin(ogen) degradation product;
atherosclerosis;
ischemic cerebrovascular disease
- From:
International Journal of Cerebrovascular Diseases
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Atherosclerosis is the most important pathological basis of ischemic cerebrovascular diseases. As an independent risk factor of atherosclerosis, fibrin(ogen) and its degradation products involve in the processes of the formation and development of atherosclerosis. This article reviews the relationship between fibrin(ogen) and/or its degradation products and atherosclerosis, and also introduces the development and application prospects for some specific motif antagonists of fibrin(ogen) in the treatment of atherosclerosis and ischemic cerebrovascular diseases.
