Detection of single nucleotide polymorphism of all coding region in ABCA1 gene and relationship among R1587K and plasma lipids and coronary artery disease
- VernacularTitle:ABCA1基因编码区SNP检测及R1587K与血脂和冠心病的关系
- Author:
Yayang LIU
;
Zhigang GUO
;
Yan TU
- Publication Type:Journal Article
- Keywords:
ATP binding cassette transporter A1;
polymorphism, single nucleotide;
genes, ABCA1;
coronary disease;
hyperlipidemia
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Conclusion The genotypes of ABCA1 R1587K polymorphism were associated closely with the plasma levels of HDL-C. The HDL-C levels of K allele carriers were remarkably lower. However, there was no significant association of the ABCA1 R1587K polymorphism and the susceptibility to CAD.