Correlation between activated blood platelet and large vascular disease in type 2 diabetes mellitus
- VernacularTitle:2型糖尿病患者大血管病变与活化血小板的相关性研究
- Author:
Na LUO
;
Yan ZHU
;
Zhenwen ZHANG
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus;
Activated blood platelet;
Large vascular disease
- From:
Chinese Journal of Practical Internal Medicine
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the association of activated blood platelet and large vacular disease in type 2 diabetes mellitus.Methods A total of 98 cases of type 2 diabetes mellitus patients were divided into two groups(50 cases with large vascular disease and 48 cases,as DM group)and 50 cases healthy subjects served as a control group.From 2002-05 to 2004-11,the doctors of the Department of Endocrinology,Subei Hospital to determined the expression of platelet activation PAC-1、CD62P in large vascular disease by technique of flow cytometry(FCM),and glycosylated hemoglobin(HbA_1c)、C-reactive protein(CRP)、fasting plasama glucose(FBG)、C-peptide(C-P)and blood lipids were measured and analysed for the correlation.Results Activated blood platelet was significantly increased in DM group as compared with that in control group(P
