Use of inflammatory markers in induced sputum in asthma severity and differential diagnosis
- VernacularTitle:诱导痰炎性标志物检测在判定哮喘严重程度和鉴别诊断中的应用
- Author:
Suping HU
;
Jiong YANG
;
Hanxiang NIE
- Publication Type:Journal Article
- Keywords:
Asthma;
COPD;
Eosinophil;
Eosinophil cationic protein
- From:
Chinese Journal of Practical Internal Medicine
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the number of eosinophil(Eos)and level of eosinophil cationic protein(ECP)in induced sputum and asthma severity and their value of differential diagnosis.Methods From July 2002 to June 2004,59 asthmatic patients were selected in the People Hospital of Wuhan University.The number of eosinophil and level of ECP were measured by Wrights' stain and Immuno-CAP System.The lung function was also evaluated.The same index was measured in 20 patients with COPD and 10 healthy subjects as control.Results The number of eosinophil in induced sputum in asthmatic patients negatively correlated with FEV_1%(r=-0.65,P
