The dynamic changes of CD_(34)~+ cell and T lymphocyte subset after using rHuG-CSF in different people
- VernacularTitle:重组人粒细胞集落刺激因子对不同人群CD_(34)~+细胞及T细胞亚群影响的动态变化研究
- Author:
Cunbang WANG
;
Yingxian OU
;
Hai BAI
- Publication Type:Journal Article
- Keywords:
rHuG-CSF;
Bone marrow;
Peripheral blood;
CD_(34)~+ cell;
T lymphocyte subset
- From:
Chinese Journal of Practical Internal Medicine
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To approach the dynamic changes of CD~+_ 34 cells and T lymphocyte subsets and best time of peripheral blood stem cell harvest when using rHuG-CSF for peripheral blood stem cell mobilization in donors and patients.Methods From 2001 to 2002 12 donors and 16 patients in Lanzhou General Hospital who received chemotherapy 7 days ago were injected rHuG-CSF 300 ?g/d for mobilization peripheral blood stem cells,and flow cytometry were used to detect the changes of CD~+_ 34 cells and T lymphocyte subsets for 5 days.Results (1)Before using rHuG-CSF,there was obvious difference between patients and donors in bone marrow CD~+_ 34 cells(P
