Study on the Antidepressant Effects and Mechanism of Hypericum Perforatum L.(EHP)in Stress-induced Depressive Model
- VernacularTitle:金丝桃提取物对应激动物模型的抗抑郁作用及其机理研究
- Author:
Xiaoming ZHONG
;
Qingqiu MAO
;
Zhen HUANG
- Publication Type:Journal Article
- Keywords:
extract of Hypericumperatum L.;
antidepressant;
forced swimming model;
tail suspension model;
chronic stress-induced depressive model;
monoamine neurotransmitters
- From:
Journal of Zhejiang Chinese Medical University
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To study the antidepressant effects and mechanism of Hypericum peratum L.(Elqe).[Methods]Forced-swimming test in mice,tail-suspension test in mice mensurating cerebracontents of monoamine neurotransmitters in chronic stress-induced depressive rats done to study the antidepressant effects and mechanism of extract of Hypericum peratum L [Results]Immobility time of forced-swimming and tail-suspension in mice which were significantly shortened by EHP (320mg/kg,160mg/kg)(P
