Adaptation of emphysema rabbit diaphragm muscle mechanics to chronic ultra-low frequency electrical stimulation and chronic physiological frequency electrical stimulation
- VernacularTitle:肺气肿兔膈肌力学模式对慢性超低频复合生理频率电刺激的适应性改变
- Author:
Xiangpeng LI
;
Junmei LI
;
Gang LIU
- Publication Type:Journal Article
- Keywords:
emphysema;
diaphragm muscle;
chronic electrical stimulation;
frequency;
mechanics
- From:Journal of Third Military Medical University
1988;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of chronic ultra-low frequency electrical stimulation on mechanical characteristic of diaphragmatic muscle of emphysema rabbit.Methods The rabbit model of emphysema was made by inhaling papain of ultrasonic atomization once a week for 3 weeks in 24 adult Japanese rabbits,6 receiving 10 Hz chronic ultra-low frequency electrical stimulation,6 receiving 40 Hz,6 receiving 2.5 Hz and 40 Hz.Another 6 rabbits served as control.The twitch tension (Pt),titanic tension(Po),time to peak tension(TPT),half-relaxation time(1/2RT),fatigue index(FI) and fatigue recovery index(FRI) were measured in control group,emphysema group,emphysema+chronic ultra-low frequency electrical stimulation groups.Results As compared with the control rabbits, Pt and Po decreased,TPT and 1/2RT prolonged,FI and FRI increased in the only emphysema rabbits.Pt and Po were higher,TPR and 1/2Rt was shorter in the only emphysema rabbits than the rabbits in 40 Hz and(2.5+40) Hz groups(P0.05),more increase in FR and FRI(P
