Change and Significance of Neutrophil Elastase (NE) and Matrix Metalloproteinase-9 (MMP-9) in Sepsis.
- VernacularTitle:中性粒细胞蛋白酶在脓毒症中的变化及临床意义
- Author:
Min YU
;
Xianzhe LIU
;
Qun DENG
- Publication Type:Journal Article
- Keywords:
Sepsis;
Multiple organ dysfunction syndrome;
Neutrophil elastase;
Matrix metalloproteinase-9
- From:
Journal of Medical Research
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the change of neutrophil elastase and matrix metalloproteinase-9 in sepsis and determine significance in the early diagnosis and prognosis of multiple organ dysfunction syndrome.Methods The plasma levels of neutrophil elastase and matrix metalloproteinase-9 in 28 ICU patients with sepsis were examined by immunofluorescence.Results Compared with control group,the levels of NE and MMP-9 were significantly higher on the day of the diagnosis of sepsis(P
